HIV-Target Cell Response in Women Initiating Various Contraceptive Methods in High HIV-Incidence Areas: Zim CHIC
Status:
Completed
Trial end date:
2020-12-01
Target enrollment:
Participant gender:
Summary
This study is being done to understand if using birth control causes changes in the immune
cells within the reproductive tract of healthy women. Immune cells are important because they
help prevent infections from starting and help fight infections that have started. Immune
cells are also the type of cells that HIV (human immunodeficiency virus) infects so
understanding more about them will help to better understand how to prevent the spread of
HIV.
Immune cells will be studied from the reproductive tract of women who want to start using one
of the following contraceptives: Depo-Provera (DMPA), NET-EN, MPA/E2 (Cyclofem®), the
levonorgestrel subdermal implant (Jadelle® ), the etonogestrel subdermal implant (Implanon®
or Nexplanon® ) and the copper IUD.