HOPE Consortium Trial to Reduce Pain and Opioid Use in Hemodialysis
Status:
Recruiting
Trial end date:
2024-05-01
Target enrollment:
Participant gender:
Summary
HOPE is a randomized clinical trial that will evaluate approaches to reducing pain and opioid
use among patients with chronic pain who are receiving maintenance hemodialysis for end-stage
renal disease. The hypothesis is that pain coping skills training will be effective at
reducing pain and opioid use, and that buprenorphine will be acceptable and tolerable as an
approach to managing physical dependence on opioids in this patient population.
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) University of Pennsylvania
Collaborators:
Durham VA Health Care System Durham VA Healthcare System Hennepin Health Care Massachusetts General Hospital New York University Rogosin Institute University of Illinois at Chicago University of New Mexico University of Pennsylvania University of Pittsburgh University of Washington VA Portland Healthcare System Vanderbilt University Medical Center West Haven VA Medical Center West Virginia University Yale University