HSV-2 Shedding Resolution After Acyclovir Treatment

• Status: Completed
• Trial end date: 2012-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to evaluate the pattern of viral shedding after beginning treatment with acyclovir for a clinical recurrence of genital herpes and to compare it with the pattern of viral shedding during an untreated clinical recurrence of genital herpes.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Washington
• Collaborator: National Institutes of Health (NIH)
• Treatments: Acyclovir

Criteria

Inclusion Criteria:

• Age 18 years or older

• History of clinically-evident genital herpes

• 3 or more clinical genital herpes recurrences within the prior 12 months

• HSV-2 seropositive by HSV Western Blot

• Willing and able to comply with study protocol

Exclusion Criteria:

• Pregnancy

• Taking daily antiviral therapy for genital herpes

• HIV seropositive or known immunocompromising medical condition

• Plan to move from the Seattle area within the next year

• Hypersensitivity to or intolerance of acyclovir