Overview

HSV-2 Suppression to Reduce Maternal HIV-1 RNA Levels During Pregnancy and Breastfeeding

Status:
Completed
Trial end date:
2010-08-01
Target enrollment:
Participant gender:
Summary
In this study, we will determine whether treating pregnant and breastfeeding women co-infected with human immunodeficiency virus type 1 (HIV-1) and herpes simplex virus type 2 (HSV-2) with daily valacyclovir will reduce HIV-1 levels in plasma, genital, and breast milk and will decrease the risk of mother-to-child HIV-1 transmission (MTCT).
Phase:
Phase 2
Details
Lead Sponsor:
University of Washington
Collaborators:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Puget Sound Partners for Global Health
Royalty Research Fund - University of Washington
Treatments:
Acyclovir
Valacyclovir