Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis- EXtended Antiplatelet Monotherapy (HOST-EXAM)
Status:
Completed
Trial end date:
2021-03-01
Target enrollment:
Participant gender:
Summary
Objectives :
To compare the efficacy and safety of clopidogrel monotherapy with aspirin monotherapy in
patients who received dual or triple antiplatelet therapy for 1 year (± 6 months) after
drug-eluting stent implantation for coronary artery disease
Patient Enrollment :
5530 patients enrolled at 55 centers in Korea
Patient Follow-up :
Clinical follow-up will occur at 1, 12 and 24 months.
Primary Endpoint :
Composite endpoint of MACE and major bleeding
Secondary Endpoint :
Device-oriented composite outcome including TLR (target lesion revascularization), TVR
(target vessel revascularization), stent thrombosis, and minor GI (gastrointestinal)
complications