Helicobacter Pylori First-line Treatment in Patients Allergic to Penicillin

• Status: Recruiting
• Trial end date: 2021-10-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to assess and compare the effectiveness of levofloxacin-tetracycline -containing and tinidazole-tetracycline-containing quadruple regimens for the primary treatment of Helicobacter pylori infection in patients allergic to penicillin.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shandong University
• Treatments: Clarithromycin; Levofloxacin; Ofloxacin; Penicillins; Tetracycline; Tinidazole

Criteria

Inclusion Criteria:

• Patients aged 18-70 with H. pylori infection.

• Patients Allergic to Penicillin.

Exclusion Criteria:

• Patients with previous H. pylori eradication therapy.

• Patients treated with Histamine-receptor antagonist, proton pump inhibitor, bismuth and antibiotics in the previous 4 weeks.

• Patients with gastrectomy, acute gastrointestinal bleeding and advanced gastric cancer.

• Patients with known or suspected allergy to study medications.

• Currently pregnant or lactating.

• Inability to provide informed consent