Overview

Helicobacter Pylori Rescue Treatment in Patients Allergic to Penicillin

Status:
Not yet recruiting
Trial end date:
2022-12-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to assess and compare the effectiveness of furazolidone-tetracycline-containing and metronidazole-tetracycline-containing quadruple regimens for the rescue treatment of Helicobacter pylori infection inpatients allergic to penicillin.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Shandong University
Treatments:
Furazolidone
Metronidazole
Criteria
Inclusion Criteria:

- Patients aged 18-70 with H. pylori infection.

- Patients with previous Helicobacter pylori eradication.

- Patients Allergic to Penicillin.

Exclusion Criteria:

- Patients treated with H2-receptor antagonist, PPI, bismuth and antibiotics in the
previous 4 weeks.

- Patients with gastrectomy, acute GI bleeding and advanced gastric cancer.

- Patients with known or suspected allergy to study medications.

- Currently pregnant or lactating.

- Inability to provide informed consent and other situations that could interfere with
the examination or therapeutic protocol.