Heliox-Powered Albuterol Therapy in the Treatment of Children Admitted With Acute Asthma Exacerbation

• Status: Terminated
• Trial end date: 2007-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to investigate whether heliox-powered albuterol nebulizer therapy will result in reduced inpatient length of stay in children hospitalized with acute asthma exacerbations.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Children's Hospital Medical Center, Cincinnati
• Treatments: Albuterol

Criteria

Inclusion Criteria:

• Age 2 -18 years;

• Previous history of asthma;

• Hospital admission for acute asthma exacerbation;

• Clinical asthma score greater than or equal to 3

Exclusion Criteria:

• Less than 2 years old or over 18 years old;

• Known allergy or hypersensitivity to ß-agonists;

• Require mechanical ventilation (invasive or non-invasive);

• Require FiO2 >0.4;

• Failure to obtain informed consent;

• Enrollment in another investigational drug or asthma protocol;

• Incipient respiratory failure including but limited to respiratory acidosis(pCO2>60 torr), altered mental status and/or excessive work of breathing.