Heliox in Experimental Upper Airway Obstruction

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Currently it is common medical wisdom that HELIOX (mixture of Helium in Oxygen) with a fraction of Helium below 60% is not effective in reducing airway obstruction. The investigators test the hypothesis that HELIOX with a fraction of Helium below 60% is still effective in relieving airway obstruction in a double-blind, randomized and controlled clinical PoC study with experimental upper airway obstruction.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Witten/Herdecke

Criteria

Inclusion Criteria:

• Volunteers of both sexes were recruited via posting in student forum of University of Witten/Herdecke

• Willingness to spend about 2h in the clinical exp. lab.

Exclusion Criteria:

• Acute airway infection

• History of asthma

• Smokers

• Pregnancy

• Abnormal lab. screen with liver function tests, Creat./BUN, CBC, blood glucose

• Anxiety or mood disorder

• Any chronic disease (incl. lung & heart disease, cancer, endocrine disorder)

• Mental retardation