Hemodynamic Effects of Terlipressin and High Dose Octreotide

• Status: Completed
• Trial end date: 2016-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to find patients's response to terlipressin and octreotide during hepatic venous pressure gradient measurement by observing portal and systemic hemodynamics.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shanghai Zhongshan Hospital
• Collaborator: Shandong Provincial Hospital
• Treatments: Lypressin; Octreotide; Terlipressin

Criteria

Inclusion Criteria:

• Gastric and Esophageal Varices have been confirmed through endoscopy

• Liver Biopsy, CT or MRI indicates cirrhosis

• Patients who experienced variceal bleeding

Exclusion Criteria:

• The patients who are beyond the range from 18 to 80 years old

• The patients with unstable vital signs

• The patients with spontaneous peritonitis or other severe infections

• The patients with hepatorenal syndrome or renal inadequacy

• The patients with uncontrolled hepatic encephalopathy

• Pregnant and lactating women

• The patients who had contraindications for terlipressin or octreotide

• The patients who refuse to take part in this study