Hemodynamic Instability Prevented With Polaramine® Infusion Before Extracorporeal Circulation
Status:
Completed
Trial end date:
2017-07-18
Target enrollment:
Participant gender:
Summary
This single-institution randomized controlled trial prospective will enrolled 48 patients
scheduled for an aortic valve replacement. The objective of the present investigation is to
determine the role of Polaramine® on reducing hemodynamic instability after separation from
cardiopulmonary bypass (CPB) during cardiac surgery. Our hypothesis is that Polaramine® play
an important role reducing dysfunction of the autonomic nervous system and hemodynamic
stability after separation from CPB.