Hemodynamics During Induction of General Anesthesia With High and Low Propofol Dose.

• Status: Completed
• Trial end date: 2020-05-31
• Target enrollment: 0
• Participant gender: Female

Summary

The study objective is to examine if a high propofol dose is non-inferior to a low dose in respect to hemodynamic stability in healthy patients during induction of general anesthesia with propofol and remifentanil.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Helse Fonna
• Treatments: Propofol

Criteria

Inclusion Criteria:

• Healthy women

• Age 18-50 years

• Gynecological procedures

• General anesthesia

Exclusion Criteria:

• Pre-existing hypertension

• Diabetes for several years

• Ischemic heart disease

• Cerebrovascular disease

• Heart valve disease

• Verified cardiac arrhythmia

• Anaemia

• Kidney or hepatic disease

• Hypersensitivity for soya, eggs or peanuts

• Pregnancy

• Poor health state

• Illicit substance use

• BMI <20 or >35 kg/m2

• SBP >150 mmHg

• HR >100 beats/min