Hemodynamics During Induction of General Anesthesia With Medium or Low Remifentanil Doses.

• Status: Recruiting
• Trial end date: 2021-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

In this trial the investigators want to examine if there is any difference in hemodynamic stability during induction when comparing two low and a medium remifentanil dose and keeping propofol induction dose at about 2.0 mg/kg.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Helse Fonna
• Treatments: Remifentanil

Criteria

Inclusion Criteria:

• Gynecological procedure

• Age 18-50 years

• General anesthesia planned

• Systolic blood pressure < 150 mmHg, HR < 100 beats/min

Exclusion Criteria:

• Pre-existing hypertension

• Diabetes

• Ischemic heart disease or cerebrovascular disease

• Heart valve disease

• Verified cardiac arrhythmia other than extrasystoles

• Verified anaemia with hemoglobin level below 9.0 gr/dl.

• Kidney or hepatic disease

• Hypersensitivity for propofol, soya, eggs or peanuts

• Pregnancy

• Poor health state

• Illicit substance use

• BMI <20 or >35 kg/m2