Hemostasis in Open Acetabulum and Pelvic Ring Surgery Using Tranexamic Acid
Status:
Completed
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
This study is investigating the use of tranexamic acid (TXA) in patients with pelvis and/or
hip socket fractures that require surgery. TXA is FDA-approved in patients with hemophilia
for short-term use to reduce hemorrhage and the need for replacement blood during tooth
extraction. However, it has also been used extensively in severely injured patients after
major trauma and during elective hip and knee replacements. Previous studies indicate TXA may
reduce blood loss and the need for blood transfusions while being safe for use in most
patients. TXA is fairly inexpensive and easy to obtain.
The purpose of this study is to determine if TXA will make surgery in patients with pelvis
and/or hip socket fractures safer and more cost efficient.