Herbal Preparation Used as Adjuvant Therapy on Diabetic Ulcers

• Status: Completed
• Trial end date: 2006-03-01
• Target enrollment: 0
• Participant gender: All

Summary

Chronic foot ulcers occurring among diabetic patients are difficult to heal. The frequent elderly age with co-morbidities, vascular insufficiencies, peripheral neuropathies and super imposed infections, all contribute towards the chronicity and failure of treatment. Preserving the ulcerated limb is the patients' wish. On the other hand, an infected ulcer that never heals just unnecessarily prolongs suffering. Nevertheless, patients earnestly like to try all methods of healing before accepting amputation.

Objective:To determine whether a course of herbal preparation used as an adjuvant therapy for diabetic patients suffering from chronic foot ulcers may promote healing so that major leg amputation can be avoided.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chinese University of Hong Kong

Criteria

Inclusion Criteria:

• Well Controlled diabetic state

• Presence of gangrene or non-healing ulcer in diabetic patients over the foot or feet. Infection should be well controlled.

• Good glycaemic control

Exclusion Criteria:

• Pregnant women and women at risk of conception

• Patients taking digitalis glycosides

• Patients with abnormal liver function tests

• Patients with plasma creatinine great then 150 umol/l or unstable renal function

• Poorly controlled Diabetes Mellitus

• Uncontrolled infection

• History of adverse reaction to herbal medicine

• Unstable medical conditions

• Non-compliance with regime