Overview

High-Dose 131I-MIBG Therapy Combined With Vincristine and Five Days of Irinotecan for Resistant/Relapsed Neuroblastoma

Status:
Completed
Trial end date:
2014-05-01
Target enrollment:
Participant gender:
Summary
This is a pilot study to determine whether doses of 15 mCi/kg and 18 mCi/kg of 131I-MIBG are tolerable when given with irinotecan/vincristine on a one week schedule to children and young adults with high-risk refractory/relapsed neuroblastoma.
Phase:
Phase 1
Details
Lead Sponsor:
University of California, San Francisco
Collaborator:
Thrasher Research Fund
Treatments:
3-Iodobenzylguanidine
Camptothecin
Irinotecan
Vincristine