Overview

High-Dose Post-Transplant Cyclophosphamide, Bortezomib, and Sitagliptin for the Prevention of GVHD

Status:
Not yet recruiting
Trial end date:
2025-12-30
Target enrollment:
Participant gender:
Summary
This is an open label Phase I-II study to determine the safe doses of bortezomib, sitagliptin, and PTCy (Phase I) with expansion into a phase II trial to determine efficacy in improving survival.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Sherif S. Farag
Treatments:
Bortezomib
Cyclophosphamide
Sitagliptin Phosphate