Overview

High Dose of Dual Therapy Plus Metronidazole for Helicobacter Pylori RescueTreatment

Status:
Completed
Trial end date:
2021-05-24
Target enrollment:
Participant gender:
Summary
Dual therapy containing high dose of proton pump inhibitor (PPI) and amoxicillin had showed excellent eradication results with Helicobacter pylori first-line treatment. However, no study has examined the the efficacy of high dose of dual therapy or dual therapy plus metronidazole for H. pylori rescue treatment.This study is designed to evaluate the efficacy and safety of the addition of metronidazole to high dose of dual therapy for H. pylori rescue treatment.
Phase:
Phase 4
Details
Lead Sponsor:
Shanghai Jiao Tong University School of Medicine
Treatments:
Amoxicillin
Esomeprazole
Metronidazole