High-voltage Pulsed Radiofrequency on Gasserian Ganglion to Treat Patients With Primary Trigeminal Neuralgia

• Status: Completed
• Trial end date: 2021-09-03
• Target enrollment: 0
• Participant gender: All

Summary

The study is designed to compare the effectiveness and safety of high-voltage Pulsed radiofrequency and nerve block for the treatment of primary Trigeminal Neuralgia patients with ineffective conservative treatment and explore better non-surgical treatment methods for Trigeminal Neuralgia patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Beijing Tiantan Hospital
• Collaborators: Beijing Ditan Hospital; Beijing Friendship Hospital

Criteria

Inclusion Criteria:

• Diagnosis of Primary Trigeminal Neuralgia meets the criteria of the International Classification of Headache Disorders.

• 18-75 years old.

• Response to drug treatment poorly or unable to tolerate the side effects of drugs.

• A BNI pain intensity scale score of IV-V.

• Supposed to undergo neurosurgical intervention according to Trigeminal Neuralgia treatment guidelines.

• Agree to participate in this trial and have signed the informed consent.

Exclusion Criteria:

• Abnormal routine blood, liver or kidney functions, abnormal blood biochemistry test, or coagulation disorders.

• Abnormal electrocardiogram or chest X-ray results.

• Severe cardiopulmonary dysfunction.

• Infection at the puncture site.

• History of mental illness, or history of narcotic drug abuse.

• Allergy to local anesthetic drugs or steroids.

• Cannot cooperate with the treatment.

• History of invasive treatments, such as radiofrequency thermocoagulation, chemical ablation, balloon compression surgery, gamma knife treatment, peripheral denervation or microvascular decompression.