High vs Low Dose Dexamethasone on Complications in the Immediate Postoperative Phase After Mastectomy
Status:
Completed
Trial end date:
2018-04-22
Target enrollment:
Participant gender:
Summary
The aim of this study is to investigate the effect of a single preoperative high-dose steroid
injection on complications in the immediate postoperative phase after breast cancer surgery,
with removal of the breast (mastectomy). Primary outcome is the proportion patients who
require transfer to the post anaesthesia care unit (PACU) and the proportion that can be
transferred directly to the ward. Secondary outcomes are organospecific complications in the
postanesthesia phase, pain and nausea the first 5 days, seroma and wound infection the first
14 days and readmissions the first 30 days after surgery.
The investigators hypothesize that the frequency of transfer to the PACU and organospecific
complications will be lower among patients receiving high dose dexamethasone. The
investigators hypothesize, that there will be no difference in wound infections, seroma or
readmissions.