Hippocampal Response to Acute Oral Doses of CBD During an fMRI Memory Task
Status:
Not yet recruiting
Trial end date:
2022-04-01
Target enrollment:
Participant gender:
Summary
Cannabidiol (CBD) is another cannabis plant derivative for which, like THC, there has been
extensive research. Unlike THC however, CBD is non-intoxicating and non-psychedelic. CBD has
antipsychotic effects. Logically, if CBD opposes THC effects, it may be a potential
antipsychotic treatment. The purpose of this pilot research is to show target engagement of
the hippocampus with the study drug (CBD versus placebo) in patients who have been diagnosed
with schizophrenia, schizoaffective disorder, or bipolar disorder with psychosis compared to
healthy controls.