Homeopathic Treatment for Depression in Peri- and Postmenopausal Women

• Status: Completed
• Trial end date: 2014-03-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this study was to determine whether individualized homeopathic treatment and fluoxetine are more efficient than placebo for moderate to severe depression in peri- and postmenopausal women.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospital Juarez de Mexico
• Treatments: Fluoxetine

Criteria

Inclusion Criteria:

• Major depression according to DSM-IV

• Moderate to severe depression according to 17-item Hamilton Rating Scale for Depression (14-24 score)

• No current use of homeopathic treatment for depression or antidepressants or anxiolytic drugs 3 months prior to study entry

• Not be currently taking psychotherapy for at least 3 months before study entry

• Early transition to menopause defined by a change in cycle length of 7 days or longer in either direction from the participant´s own baseline for at least 2 cycles

• Late transition to menopause defined as 3 to 11 months of amenorrhea

• Postmenopausal stage defined by 12 months or more of amenorrhea

• Capability and willingness to give informed consent and to comply with the study procedures

Exclusion Criteria:

• Pregnancy or breastfeeding

• Other psychiatric disorders different from moderate to severe depression (severe depression, schizophrenia, psychotic disorders, bipolar affective disorders, suicide attempt)

• Alcohol or other substance abuse

• Known allergy to fluoxetine

• Cancer or hepatic diseases