Overview

Hormonal Mechanisms of Sleep Restriction - Axis Study in Older Men and Postmenopausal Women

Status:
Recruiting
Trial end date:
2023-07-24
Target enrollment:
Participant gender:
Summary
The purpose of this study is to 1) determine how hypothalamic-pituitary-adrenal axis (HPA axis) activation occurs with sleep restriction and 2) evaluate how hypothalamic-pituitary-gonadal axis (HPG axis) deactivation occurs with sleep restriction. The investigator will also examine the cognitive function associated with sleep restriction, including food intake and food cravings.
Phase:
Early Phase 1
Details
Lead Sponsor:
Los Angeles Biomedical Research Institute
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Treatments:
BB 1101
Corticotropin-Releasing Hormone
Cosyntropin
Dexamethasone
Dexamethasone acetate
Ganirelix
Hormones
Hydrocortisone
Hydrocortisone 17-butyrate 21-propionate
Hydrocortisone acetate
Hydrocortisone hemisuccinate
Ketoconazole
Pharmaceutical Solutions
Prolactin Release-Inhibiting Factors