Hormonal Therapy and Chemotherapy Followed by Prostatectomy in Patients With Prostate Cancer
Status:
Terminated
Trial end date:
2017-09-14
Target enrollment:
Participant gender:
Summary
This is a study for men who have locally-advanced prostate cancer and are eligible to undergo
prostatectomy. Standard treatment is prostatectomy alone, but there is a chance that cancer
may spread to other organs in the future, even after the prostate is removed. If this were to
occur, standard treatment would be androgen deprivation therapy (ADT; hormone therapy that
blocks testosterone) plus chemotherapy. Clinical trials suggest that neoadjuvant treatment
(treatment given before primary therapy) may prevent a recurrence. The purpose of this
research study is to assess the safety and benefit of ADT plus chemotherapy given before
prostate removal.
Phase:
Phase 2
Details
Lead Sponsor:
The University of Texas Health Science Center, Houston