Hormone Therapy Compared With Combination Chemotherapy in Treating Patients With Prostate Cancer
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Androgens can stimulate the growth of prostate cancer cells. Drugs such as
ketoconazole may stop the production of androgens. Drugs used in chemotherapy use different
ways to stop tumor cells from dividing so they stop growing or die. It is not yet known
whether hormone therapy is more effective than combination chemotherapy in treating prostate
cancer.
PURPOSE: Randomized phase III trial to compare the effectiveness of hormone therapy with that
of combination chemotherapy in treating patients who have prostate cancer that has been
previously treated with androgen suppression.
Phase:
Phase 3
Details
Lead Sponsor:
Eastern Cooperative Oncology Group
Collaborators:
Cancer and Leukemia Group B National Cancer Institute (NCI) Southwest Oncology Group