Overview

Hormone Therapy With or Without Surgery or Radiation Therapy in Treating Patients With Prostate Cancer

Status:
Completed
Trial end date:
2012-01-06
Target enrollment:
Participant gender:
Summary
RATIONALE: Hormones can stimulate the growth of prostate cancer cells. Hormone therapy may fight prostate cancer by reducing the production of androgens. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known whether hormone therapy plus surgery is more effective than hormone therapy plus radiation therapy for prostate cancer. PURPOSE: This randomized phase III trial is studying giving hormone therapy alone to see how well it works compared to giving hormone therapy together with bilateral orchiectomy or radiation therapy in treating patients with stage III or stage IV prostate cancer.
Phase:
Phase 3
Details
Lead Sponsor:
NCIC Clinical Trials Group
Collaborators:
Eastern Cooperative Oncology Group
Medical Research Council
National Cancer Institute (NCI)
Southwest Oncology Group
Treatments:
Androgens
Bicalutamide
Buserelin
Flutamide
Goserelin
Leuprolide
Nilutamide