Hormones Inflammation and Thrombosis

• Status: Terminated
• Trial end date: 2013-11-01
• Target enrollment: 0
• Participant gender: Female

Summary

The investigators are attempting to determine if the response to aspirin in women is related to the level of estrogen and progesterone that a woman has.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Johns Hopkins University
• Treatments: Aspirin; Hormones

Criteria

Inclusion Criteria:

1. Women age 18-80

2. Signed informed consent.

Exclusion Criteria:

1. History of CAD, Cerebrovascular Accident (CVA) or Peripheral Artery Disease (PAD),

2. On chronic aspirin therapy,

3. On chronic NSAID therapy.

4. Chronic anticoagulation with coumadin,

5. Known thrombocytopenia (Platelet count < 100,000),

6. Pregnancy (self-report),

7. Currently on any type of contraceptive or hormone replacement therapy,

8. Hysterectomy and/or oophorectomy.

9. Recent GI bleeding

10. Bleeding diathesis

11. Chronic Systemic Infection