Houston Emergency Opioid Engagement System

• Status: Recruiting
• Trial end date: 2022-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The Houston Emergency Response Opioid Engagement System (HEROES) is a community-based research program integrating assertive outreach, medication-assisted treatment, behavioral counseling, peer recovery support, and paramedic follow-up in Houston Texas. The objective is to compare differences in engagement and retention in treatment for individuals with opioid use disorder.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The University of Texas Health Science Center, Houston
• Treatments: Buprenorphine, Naloxone Drug Combination

Criteria

Inclusion Criteria:

• In otherwise good health based on physician assessment and medical history

• Tests positive in urine sample for opioids

• Patients express a willingness to stop opioid use

• Meet Diagnostic and Statistical Manual of Mental Disorders - Text Revision (DSM-IV-TR) criteria for opioid dependence

• Patients must be able to speak English

• Be agreeable to and capable of signing informed consent

Exclusion Criteria:

• Non-English-speaking patients

• Have a known sensitivity to buprenorphine or naloxone

• Be physiologically dependent on alcohol, benzodiazepines or other drugs of abuse that require immediate medical attention. Other substance use diagnoses are not exclusionary.

• Have a medical condition that would, in the opinion of the study physician, make participation medically hazardous, including unstable cardiovascular disease, neurological deficits, trauma, acute hepatitis, stroke, and liver or renal disease)

• Be acutely psychotic, severely depressed, and in need of inpatient treatment, or is an immediate suicide risk

• Be a nursing or pregnant female