How Different Sedatives Affect Hip Fracture Patient's Postoperative Delirium
Status:
Unknown status
Trial end date:
2019-06-30
Target enrollment:
Participant gender:
Summary
the hypothesis is that Dexmedetomidine seems to decrease incidence of post-operative delirium
. one possible mechanism is that Dex have a minor influence on cognition, since it has no
effect on GABA receptor，another is that Dex could induce a sleep similar to natural sleep,
thereby decreasing sleep deprivation and circadian rhythm disorder in post-operative
patients.
In this study , investigators devise the two different sedatives(Dexmedetomidine and
Propofol)'influence on postoperative delirium in hip fracture elderly participants under
spinal anesthesia
Phase:
Phase 4
Details
Lead Sponsor:
Shanghai Zhongshan Hospital
Collaborators:
Beijing Jishuitan Hospital First Affiliated Hospital of Guangxi Medical University Foshan Hospital of Traditional Chinese Medicine Qianfoshan Hospital Second Hospital of Shanxi Medical University Shanghai 6th People's Hospital Shanghai Changzheng Hospital Tang-Du Hospital The First Affiliated Hospital of Nanchang University The First Affiliated Hospital of Soochow University The Fuzhou No 2 Hospital The Second Affiliated Hospital of Harbin Medical University