Human Brain Natriuretic Peptide (BNP) (or Nesiritide) to Help Heart, Kidney and Humoral Function.
Status:
Completed
Trial end date:
2012-08-01
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to evaluate the effects of cardiac hormone replacement
with SQ (subcutaneous or under the skin) injection of BNP (brain natriuretic peptide, a
hormone produced by the heart) on the pumping ability of the heart, kidney function and
levels of different hormones in the blood in response to an intravenous salt solution.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Mayo Clinic
Collaborators:
National Center for Research Resources (NCRR) National Heart, Lung, and Blood Institute (NHLBI) National Institutes of Health (NIH) Scios, Inc.