Human Umbilical Cord Mesenchymal Stem Cells Treatment for Lupus Nephritis (LN)
Status:
Unknown status
Trial end date:
2021-06-01
Target enrollment:
Participant gender:
Summary
Lupus nephritis (LN) is one of the most serious complications and the main cause of death in
patients with systemic lupus erythematosus (SLE).The investigators have investigated the
usefulness, and confirmed the efficacy and safety of mesenchymal stem cells (MSC) treatment
of LN in animal models, in vitro experiments and phase I clinical trial. In this study, a
randomized, placebo-controlled, parallel group, non-inferiority, prospective, multicenter
clinical trial is performed to investigate the efficacy and safety of MSC transplantation in
the treatment of LN compared to mycophenolate mofetil (MMF).