Hyaluronic Acid in Acute Exacerbation of COPD - Duration Of Noninvasive Assistance

• Status: Completed
• Trial end date: 2019-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this study is to test the effect of High Molecular Weight Hyaluronic Acid (HMW-HA) on Non Invasive Ventilation (NIV) effectiveness in patients admitted to a sub-intensive care unit for respiratory failure due to acute exacerbation of Chronic Obstructive Pulmonary Disease (COPD).

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Campus Bio-Medico University
• Collaborator: National Institute of Environmental Health Sciences (NIEHS)
• Treatments: Hyaluronic Acid

Criteria

Inclusion Criteria:

• Aged 18 years of age or older

• Admitted for respiratory failure primarily due to COPD exacerbation

• Requiring non-invasive ventilation

• Respiratory distress, as evidenced by moderate-to-severe dyspnea and use of accessory muscles of respiration

• Hypercapnic respiratory failure

• High respiratory rate

Exclusion Criteria:

• Respiratory arrest or the need for immediate intubation

• Upper airways obstruction

• Facial trauma

• Inability to cooperate