Hydrocodone Compared to Acetaminophen and Ibuprofen for Post-nail Procedure Analgesia

• Status: Not yet recruiting
• Trial end date: 2023-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to assess the safety and efficacy of ropivacaine and hydrocodone for nail-procedure associated pain management. The investigators hypothesize that ropivacaine with hydrocodone will be superior to ropivacaine with acetaminophen and ibuprofen for managing pain.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Weill Medical College of Cornell University
• Treatments: Acetaminophen; Hydrocodone; Ibuprofen

Criteria

Inclusion Criteria:

• Patients undergoing fingernail or toenail, excision, or shave biopsy

• Must understand and voluntarily sign an informed consent form

• Must be male or female and aged 18-95 years at time of consent

• Must be able to adhere to the study visit schedule and other protocol requirements

Exclusion Criteria:

• Subject is unable to provide written informed consent for any reason

• Subject has peripheral vascular disease, arterial insufficiency, peripheral neuropathy

• Subject is on Aspirin, NSAIDs, or consumes a chronic medication for control of any other chronic pain

• Subject has a history of opioid or alcohol use disorder

• Subject has a history of peptic ulcer disease, gastritis, chronic renal insufficiency or a history of kidney disease, or has underlying liver disease

• Subject has a history of severe constipation

• Subject is sensitive or allergic to any of the elements included in this study

• Subject is unable to complete the required pain dairy

• Subject is pregnant, planning pregnancy, or nursing