Hydroxychloroquine, Abemaciclib and Endocrine Therapy in Hormone Receptor Positive (HR+)/Her 2 Negative Breast Cancer
Status:
Recruiting
Trial end date:
2028-01-01
Target enrollment:
Participant gender:
Summary
The hypothesis is that abemaciclib synergizes with autophagy inhibitor hydroxychloroquine
(HCQ/ Plaquenil), inducing apoptosis leading to tumor regression.