Hydroxychloroquine to Prevent SARS-CoV-2 Infection/COVID-19
Status:
Completed
Trial end date:
2020-11-23
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine whether hydroxychloroquine is an effective
prophylactic regimen to prevent SARS-CoV-2 infection among healthcare workers. Participants
will be randomized into two parallel groups. The first arm will evaluate the use of
hydroxychloroquine every-other-day plus standard measures of protection for the prevention of
SARS-CoV-2. The second arm will evaluate the use of standard measures of protection for the
prevention of SARS-CoV-2. The target enrollment is 320 participants. Each study participant
will be monitored for SARS-CoV-2 seroconversion in weekly visits or for the development of
COVID-19 symptoms for 8 weeks.