Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones

• Status: Recruiting
• Trial end date: 2028-08-31
• Target enrollment: 0
• Participant gender: All

Summary

This study tests whether hydroxycitrate, a molecule closely related to citrate, can reduce calcium phosphate stone recurrence.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Texas Southwestern Medical Center
• Treatments: Potassium Citrate

Criteria

Inclusion Criteria:

• Calcium Phosphate stone formers

Exclusion Criteria:

• History of recurrent urinary tract infections

• Chronic diarrhea

• Estimated Glomerular Filtration Rate (eGFR) < 45 ml/min/1.73 m2

• History of primary hyperparathyroidism

• Hypokalemia

• Hyperkalemia

• Pregnancy