Hyperhidrosis, Developing a Treatment Approach Aims 1 & 2
Status:
Active, not recruiting
Trial end date:
2022-12-30
Target enrollment:
Participant gender:
Summary
The objective is to establish an evidence base for a hyperhidrosis treatment algorithm in
amputees. This project will address a problem that has troubled Service members, Veterans,
and civilians with amputations for decades, impacting satisfaction with prosthetic use,
residual limb skin health, and negatively affecting quality of life. Prior research in this
area has been limited and insufficient. The Investigators are confident that improving the
evaluation and treatment of residual limb hyperhidrosis will reduce the secondary health
consequences of amputation and will lead to improved quality of life. This will be accomplish
by completing the following specific aims.
Aim 1: Test the validity of the Minor iodine-starch test in amputees. Hypothesis: The
iodine-starch test is a valid diagnostic tool of hyperhidrosis and can be useful for the
identification of focal areas of sweating on a residual limb Aim 2: Test the effectiveness of
a prescription strength topical antiperspirant (Aluminum Chloride 20%) on hyperhidrosis of
the residual limb.
Hypothesis: Aluminum Chloride will be more effective at controlling sweating than placebo
Phase:
Phase 1
Details
Lead Sponsor:
Colby Hansen University of Utah
Collaborators:
U.S. Army Medical Research and Development Command US Department of Veterans Affairs