Assessment of the effect of hyperoxia and hypertonic saline on survival in patients with
septic shock Hyperoxia and hypertonic saline may have beneficial effects on organ perfusion
and oxygenation and may reduce the organ failure occurences. To date, only scarce data are
available. Side effects are not well described. Therefore we designed a randomized clinical
trial in order to assess the early administration of hypertonic saline and oxygen in the very
early beginning of septic shock.