Hyperproteic Diet Plus Lactobacillus Reuteri and Nitazoxanide in Minimal Hepatic Encephalopathy
Status:
Completed
Trial end date:
2014-07-01
Target enrollment:
Participant gender:
Summary
Hepatic encephalopathy is a serious complication of cirrhosis which relays under the burden
of diseases with therapeutical difficulties for its given morbidity and mortality and the
high recurrence it poses. Its treatment remains a challenge for most of the cases. Even more,
minimal hepatic encephalopathy is an entity that has an additional morbidity for it being a
subclinical entity. As so, the investigators propose an auxiliary treatment for the
management of such patients with minimal hepatic encephalopathy, using a specific diet
consisting on hyperproteic and fibre-rich foods along with two independent interventions,
whether a probiotic, lactobacillus reuteri, or a drug, nitozoxanide, so to diminish the rate
of progression to any clinical stage of hepatic encephalopathy and to revert minimal hepatic
encephalopathy itself to none hepatic encephalopathy.
Phase:
N/A
Details
Lead Sponsor:
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran