Hypertension Monitoring in Glioma Patients Treated With Bevacizumab
Status:
Terminated
Trial end date:
2012-08-01
Target enrollment:
Participant gender:
Summary
Prospective casecontrol study in glioma patients undergoing treatment with bevacizumab
(Avastin). At present there are no data on the correlation between occurrence of arterial
hypertension and clinical outcome in patients with glioma or anaplastic astrocytoma. We will
investigate whether glioma patients developing hypertension under bevacizumab treatment have
a better outcome in terms of progression free survival, response rate and overall survival
than equally treated patients remaining normotensive. Moreover, we will describe the dynamics
of change in blood pressure after administration of bevacizumab in those patients developing
hypertension.
- Trial with medicinal product