Hypertonic Saline With Dextran for Treating Hypovolemic Shock and Severe Brain Injury
Status:
Completed
Trial end date:
2007-03-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate the clinical outcome of patients following blunt
traumatic injury with hypovolemic shock, who receive either lactated ringer's solution or
hypertonic saline with dextran (HSD) resuscitation; also, to focus specifically on neurologic
outcome in patients with brain injury and on the effect of HSD resuscitation on inflammatory
cell responsiveness.