Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mellitus
Status:
Completed
Trial end date:
2018-10-09
Target enrollment:
Participant gender:
Summary
Elevations of plasma cortisol, a stress hormone, during prior episodes of low blood sugar
(hypoglycemia) appear to be responsible for the deficient responses during subsequent
hypoglycemia. Our specific aim is to determine if dehydroepiandrosterone (DHEA), a hormone
with anti-corticosteroid actions, can prevent hypoglycemia associated autonomic failure in
type 1 diabetic volunteers.
Phase:
Early Phase 1
Details
Lead Sponsor:
University of Maryland University of Maryland, Baltimore
Collaborator:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)