Overview

IDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal Melanoma

Status:
Recruiting
Trial end date:
2028-01-15
Target enrollment:
Participant gender:
Summary
This is a Phase 2/3, multi-arm, multi-stage, open-label study of human leukocyte antigen (HLA)-A*02:01 negative participants with metastatic uveal melanoma (MUM) who will be randomized to receive either IDE196 + crizotinib or investigator's choice of treatment (pembrolizumab, ipilimumab + nivolumab, or dacarbazine).
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
IDEAYA Biosciences
Treatments:
Crizotinib
Dacarbazine
Ipilimumab
Nivolumab
Pembrolizumab