Overview

IO-202 as Monotherapy in Patients in AML and CMML

Status:
Recruiting
Trial end date:
2024-03-01
Target enrollment:
Participant gender:
Summary
To assess safety and tolerability at increasing dose levels of IO-202 in successive cohorts of participants with relapsed or refractory monocytic AML and CMML in order to estimate the maximum tolerated dose (MTD) or maximum administered dose (MAD) and select the recommended Phase 2 dose (RP2D) and dose schedule as monotherapy.
Phase:
Phase 1
Details
Lead Sponsor:
Immune-Onc Therapeutics Inc
Collaborator:
California Institute for Regenerative Medicine (CIRM)
Treatments:
Azacitidine