IOP Changes With Different Anesthetic Agents During Laparoscopic Colorectal Surgery
Status:
Completed
Trial end date:
2017-03-08
Target enrollment:
Participant gender:
Summary
This study is aimed to evaluate how intraocular pressure (IOP) is changed depending on
surgical position (Trendelenburg versus reverse Trendelenburg) in the same patient and to
compare the effects of different anesthetics on IOP (desflurane versus propofol) in patients
undergoing laparoscopic colorectal surgery. The study design is a double-blind randomized
controlled trial. The patients were randomly assigned to desflurane or propofol administrated
groups and all patient are administered intravenous remifentanil continuously as adjuvant
analgesics during anesthesia. For this study 50 to 80-year-old patients undergoing
laparoscopic colorectal surgery without eye disease were enrolled. Mean arterial blood
pressure, peak airway pressure, end tidal carbon dioxide, and IOP (using a Tono-pen® Avia
tonometer) on both eyes were measured at defined intervals during the procedure.