Overview

IRIS Followed by mFOLFOX6 or the Reverse Sequence in Advanced Colorectal Cancer

Status:
Suspended
Trial end date:
2009-03-01
Target enrollment:
Participant gender:
Summary
This randomized phase III study compares safety and efficacy of two sequence arms in advanced colorectal cancer: irinotecan and S-1 (IRIS) followed by oxaliplatin containing regimen (arm A), or l-leucovorin (l-LV), 5-FU and oxaliplatin (mFOLFOX6) followed by irinotecan containing regimen (arm B).
Phase:
Phase 3
Details
Lead Sponsor:
Hokkaido Gastrointestinal Cancer Study Group
Collaborator:
Hokkaido University Hospital
Treatments:
Camptothecin
Fluorouracil
Irinotecan
Leucovorin
Levoleucovorin
Oxaliplatin