IV Acetaminophen for Postoperative Analgesia

• Status: Terminated
• Trial end date: 2015-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the use of IV acetaminophen for postoperative pain management after laparoscopic cholecystectomy to determine if its use to supplement standard of care pain management decreases the incidence of post-operative nausea and vomiting.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Northwell Health
• Treatments: Acetaminophen

Criteria

Inclusion Criteria:

• Subject is undergoing pre-scheduled laparoscopic cholecystectomy;

• American Society of Anesthesiology patient classification status I-II

Exclusion Criteria:

• Regular preoperative use of or opioids,

• Subjects admitted after surgery for postoperative complications other than postoperative pain or PONV.

• Subjects converted to open laparoscopic cholecystectomy

• Known allergy/hypersensitivity to acetaminophen

• Use of opioids prior to commencement of the study (<7 days)

• Patients with chronic pain conditions or disease requiring pain control

• Abnormal liver function

• Known or suspected alcohol, drug or opiate abuse or dependence

• Patients with a BMI of greater than 35

• Other physical, mental or medical conditions that could effect participation.

• Abnormal renal function; serum creatinine>2gm/dl