IV Glucose for Dehydration Treatment

• Status: Completed
• Trial end date: 2012-03-01
• Target enrollment: 0
• Participant gender: All

Summary

To determine whether the addition of dextrose to IV fluids in the treatment of gastroenteritis leads to a decrease in serum ketones. Secondarily, the clinical benefits of dextrose containing fluids in the treatment of gastroenteritis will be assessed.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Children's Hospital of Philadelphia
• Collaborators: Academic Pediatric Association; American Academy of Pediatrics

Criteria

Inclusion Criteria:

1. Males or females age 2 months to 12th birth date

2. Gastroenteritis (as diagnosed by ED attending or fellow physician)

3. Need for IV fluids

4. Dextrose stick of greater than 60 and less than 170

5. Parental/guardian English speaking and granting informed consent

Exclusion Criteria:

1. Underlying chronic disease affecting glucose metabolism or reason/persistence of symptoms: Renal failure, Diabetes Mellitus, Diabetes Insipidus, Metabolic Disorder, VP shunt, Migraine Headaches

2. Shock

3. Vomiting greater than 72 hours since onset of illness

4. Patients that have received IV fluids at an outside institution within 12 hours