Overview

Ibrutinib and Lenalidomide With Dose Adjusted EPOCH-R in Subjects With Relapsed/Refractory Diffuse Large B-cell Lymphoma

Status:
Completed
Trial end date:
2017-08-01
Target enrollment:
Participant gender:
Summary
This is a Phase 1b/2, open-label, non-randomized multicenter study to assess the safety and efficacy of ibrutinib and lenalidomide in combination with DA-EPOCH-R in subjects with relapsed/refractory Diffuse Large B-cell Lymphoma (DLBCL).
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Pharmacyclics LLC.
Collaborator:
Celgene Corporation
Treatments:
Cyclophosphamide
Doxorubicin
Etoposide
Etoposide phosphate
Lenalidomide
Liposomal doxorubicin
Prednisone
Rituximab
Thalidomide
Vincristine