Ibuprofen Plus Acetaminophen Versus Oxycodone Alone After Hand Surgery

• Status: Completed
• Trial end date: 2019-05-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is about pain control and medication following outpatient soft-tissue hand surgery. We hope to learn if ibuprofen and acetaminophen will achieve similar pain relief and satisfaction when compared with oxycodone alone.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Southern California
• Treatments: Acetaminophen; Ibuprofen; Oxycodone

Criteria

Inclusion Criteria:

• age greater than 18 years

• scheduled to undergo elective outpatient soft tissue hand surgery for one of the following procedures: Carpal tunnel release, Dupuytren contracture release, trigger digit release, ganglion cyst removal, de Quervain's release.

• primary language is English or Spanish

Exclusion Criteria:

• any pre-existing condition requiring preoperative opiate analgesia, eg chronic pain syndrome

• allergy to acetaminophen, ibuprofen, or oxycodone

• renal impairment or liver disease either documented based on history or when preoperative creatinine, BUN, or liver function tests are outside the normal range provided by the lab

• peptic ulcer disease or any history of gastrointestinal bleeding

• coagulopathy documented on history, review of systems, or based on preoperative lab testing where PT, PTT, or INR are outside the normal range provided by the lab

• pregnancy based on positive beta-HCG test which is performed on the day of the surgical procedure as is standard protocol